Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 6/20 | 0.45 |
| ▸ | RARG | P13631 | 6/20 | 0.45 |
| ▸ | RARA | P10276 | 6/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.45 |
| ▸ | VDR | P11473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028156 | 0.86 | RARA (0.60) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL8771845 | 0.85 | PTPN1 (0.52) | PTPN1RARBRARGRARARXRA | |
| SCHEMBL8771839 | 0.85 | PTPN1 (0.52) | PTPN1RARBRARGRARARXRA | |
| SCHEMBL8026383 | 0.84 | CYP3A4 (0.42) | RARBRARGRARARXRAMAPT | |
| SCHEMBL6814374 | 0.83 | RARA (0.42) | PTPN1RARBRARGRARARXRA | |
| SCHEMBL6814367 | 0.83 | RARA (0.42) | PTPN1RARBRARGRARARXRA | |
| SCHEMBL6814451 | 0.82 | PTPN1 (0.42) | PTPN1RARBRARGRARARXRA | |
| SCHEMBL6814443 | 0.82 | PTPN1 (0.42) | PTPN1RARBRARGRARARXRA | |
| SCHEMBL8028176 | 0.82 | RARB (0.43) | RARBRARGRARARXRAMAPT | |
| SCHEMBL8026631 | 0.81 | RARB (0.56) | PTPN1RARBRARGRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059861-A1 | SELECTIVE RETINOIC ACID ANALOGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |