Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.59 |
| ▸ | RARB | P10826 | 11/20 | 0.59 |
| ▸ | RARG | P13631 | 10/20 | 0.59 |
| ▸ | RARA | P10276 | 6/20 | 0.59 |
| ▸ | RXRB | P28702 | 5/20 | 0.59 |
| ▸ | RXRG | P48443 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028176 | 0.86 | RARB (0.43) | RXRARARBRARGRARARXRB | |
| SCHEMBL8028156 | 0.81 | RARA (0.60) | RXRARARBRARGRARARXRB | |
| SCHEMBL6813834 | 0.81 | RXRA (0.49) | RXRARARBRARGRARARXRB | |
| SCHEMBL8026327 | 0.79 | RARB (0.59) | RXRARARBRARGRARARXRB | |
| SCHEMBL8771700 | 0.76 | RXRA (0.67) | RXRARARBRARGRARARXRB | |
| SCHEMBL6818089 | 0.75 | RXRA (1.00) | RXRARARBRARGRARARXRB | |
| SCHEMBL7800377 | 0.73 | RARB (0.55) | RXRARARBRARGRARARXRB | |
| SCHEMBL8032216 | 0.73 | RARB (0.55) | RXRARARBRARGRARARXRB | |
| SCHEMBL7635603 | 0.73 | RARB (0.71) | RXRARARBRARGRARARXRB | |
| SCHEMBL7811799 | 0.73 | RARB (0.69) | RXRARARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059861-A1 | SELECTIVE RETINOIC ACID ANALOGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-12 | — | — | WO | claimed |