Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 13/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022761 | 0.90 | PLA2G1B (0.66) | PLA2G1BSCD | |
| SCHEMBL7007813 | 0.85 | PLA2G1B (0.66) | PLA2G1BKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8323820 | 0.84 | PLA2G1B (0.51) | PLA2G1B | |
| SCHEMBL7048835 | 0.80 | PLA2G1B (0.86) | PLA2G1B | |
| SCHEMBL8071903 | 0.79 | PLA2G1B (0.59) | PLA2G1BSCD | |
| SCHEMBL8022570 | 0.77 | PLA2G1B (0.48) | PLA2G1BKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8012905 | 0.76 | PLA2G1B (0.60) | PLA2G1B | |
| SCHEMBL7013828 | 0.76 | PLA2G1B (0.67) | PLA2G1B | |
| SCHEMBL5000568 | 0.73 | PTGDR2 (0.47) | PLA2G1BPPARGPPARDPPARASCD | |
| SCHEMBL9080274 | 0.72 | PLA2G1B (0.45) | PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977566-A1 | METHOD FOR THE TREATMENT OF STROKE USING N-HETEROCYCLIC GLYOXYLAMIDE COMPOUNDS | SHIONOGI & CO., LTD. (JP) | 2000-02-09 | — | — | EP | claimed |
| WO-1998047508-A1 | METHOD FOR THE TREATMENT OF STROKE USING N-HETEROCYCLIC GLYOXYLAMIDE COMPOUNDS | SHIONOGI & CO., LTD. (JP) | 1998-10-29 | — | — | WO | claimed |
| EP-0977566-A1 | METHOD FOR THE TREATMENT OF STROKE USING N-HETEROCYCLIC GLYOXYLAMIDE COMPOUNDS | SHIONOGI & CO., LTD. (JP) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998047508-A1 | METHOD FOR THE TREATMENT OF STROKE USING N-HETEROCYCLIC GLYOXYLAMIDE COMPOUNDS | SHIONOGI & CO., LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |