Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014844 | 0.88 | ATM (0.48) | PLA2G1BPTGER1MRGPRX4MAOB | |
| SCHEMBL7006665 | 0.85 | PLA2G1B (0.43) | PLA2G1BPTGER1MRGPRX4NR4A2 | |
| SCHEMBL7005845 | 0.84 | ABCB1 (0.47) | PLA2G1BMRGPRX4NR4A2VNN1MAOB | |
| SCHEMBL8323820 | 0.83 | PLA2G1B (0.51) | PLA2G1BPTGER1NR4A2MAOBPPIA | |
| SCHEMBL8327075 | 0.83 | PLA2G1B (0.52) | PLA2G1BPTGER1MRGPRX4NR4A2VNN1 | |
| SCHEMBL8320616 | 0.82 | MRGPRX4 (0.45) | PLA2G1BPTGER1MRGPRX4FFAR4 | |
| SCHEMBL7011444 | 0.82 | ATP4A (0.43) | PLA2G1BMRGPRX4 | |
| SCHEMBL7016240 | 0.82 | ATM (0.44) | PLA2G1BPTGER1MRGPRX4 | |
| SCHEMBL8321751 | 0.77 | L3MBTL1 (0.46) | PLA2G1BPTGER1MRGPRX4 | |
| SCHEMBL7005971 | 0.77 | MRGPRX4 (0.45) | PLA2G1BMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996003383-A1 | INDOLIZINE sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |