Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 20/20 | 0.53 |
| ▸ | CHRM3 known ✓ | P20309 | 16/20 | 0.53 |
| ▸ | CHRM1 known ✓ | P11229 | 12/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 15/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 13/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL286149 | 0.86 | CHRM2 (0.67) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL9749642 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL10723477 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL42703 | 0.86 | — | — | |
| Water SCHEMBL8028259 | 0.84 | CHRM2 (0.64) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL28069007 | 0.84 | CHRM2 (0.64) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL286148 | 0.84 | CHRM2 (0.64) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| SCHEMBL33571 | 0.83 | — | — | |
| Alcohol SCHEMBL28442235 | 0.82 | CHRM2 (0.57) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| Methyl Alcohol SCHEMBL10541004 | 0.81 | CHRM2 (0.61) | CHRM2CHRM3CHRM5CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422280-A | Method for detecting detergent compositions for enhanced silicone deposition comprising silicone and cationic polymers | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1995-06-06 | — | — | US | claimed |
| CN-111733600-A | Preparation method of tobacco-based cellulose nanofiber | 天津科技大学 | 2020-10-02 | — | — | CN | disclosed |
| US-6117828-A | COMPRISING ANIONIC, NONIONIC, ZWITTERIONIC/AMPHOTERIC SURFACTANTS, CATIONIC WHEAT PROTEIN AND ANTIBACTERIAL AGENT; FOR CLEANING; SKIN FEEL | UNILEVER HOME & PERSONAL CARE USA (US) | 2000-09-12 | — | — | US | disclosed |
| WO-1999056721-A1 | LIQUID COMPOSITIONS COMPRISING HIGH LEVELS OF ALKYL ARYL SULFONATES | UNILEVER PLC (GB) | 1999-11-11 | — | — | WO | disclosed |
| WO-1997017310-A1 | REVERSIBLE CHARGE-BASED SEQUESTRATION ON SOLID SUPPORT | VERSICOR, INC. (US) | 1997-05-15 | — | — | WO | disclosed |
| US-5605616-A | Reversible charge-based sequestration on solid support | VERSICOR, INC. (US) | 1997-02-25 | — | — | US | disclosed |
| US-5422280-A | Method for detecting detergent compositions for enhanced silicone deposition comprising silicone and cationic polymers | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1995-06-06 | — | — | US | disclosed |