Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | PTPRG | P23470 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6720098 | 0.79 | HSD17B10 (0.62) | MAPTTSHRMEN1ALDH1A1CYP1A2 | |
| SCHEMBL6720093 | 0.79 | HSD17B10 (0.62) | MAPTTSHRMEN1ALDH1A1CYP1A2 | |
| SCHEMBL9775967 | 0.78 | MAPT (0.64) | FDPSMAPTTSHRMEN1ALDH1A1 | |
| SCHEMBL9422794 | 0.78 | MAPT (0.64) | FDPSMAPTTSHRMEN1ALDH1A1 | |
| SCHEMBL7107116 | 0.78 | MAPT (0.64) | FDPSMAPTTSHRMEN1ALDH1A1 | |
| SCHEMBL6674277 | 0.77 | BLM (0.59) | MAPTTSHRMEN1ALDH1A1CYP1A2 | |
| SCHEMBL6725266 | 0.77 | BLM (0.59) | MAPTTSHRMEN1ALDH1A1CYP1A2 | |
| SCHEMBL31212623 | 0.76 | HIF1A (0.50) | TSHRMEN1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL498294 | 0.76 | HIF1A (0.50) | TSHRMEN1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL28140995 | 0.76 | HIF1A (0.50) | TSHRMEN1ALDH1A1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973724-A1 | NOVEL PROCESS FOR THE PREPARATION OF (+/-)3- (3,4-DICHLOROPHENYL)-2- DIMETHYLAMINO-2-METHYLPROPAN-1-OL OR CERICLAMINE (INN) | PARKE-DAVIS (FR) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998045248-A1 | NOVEL PROCESS FOR THE PREPARATION OF (+/-)3- (3,4-DICHLOROPHENYL)-2- DIMETHYLAMINO-2-METHYLPROPAN-1-OL OR CERICLAMINE (INN) | JOUVEINAL (FR) | 1998-10-15 | — | — | WO | disclosed |