Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018444 | 0.99 | ALDH1A1 (0.41) | MEN1KMT2ANPSR1CYP1A2ALDH1A1 | |
| SCHEMBL15106304 | 0.84 | CYP1A2 (0.43) | MEN1KMT2ANPSR1CYP1A2ALDH1A1 | |
| SCHEMBL5980955 | 0.81 | ALDH1A1 (0.39) | MEN1KMT2ANPSR1CYP1A2ALDH1A1 | |
| SCHEMBL28667809 | 0.76 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1SLC6A3 | |
| SCHEMBL5981838 | 0.75 | ENPP2 (0.46) | MEN1KMT2AALDH1A1SLC6A3 | |
| SCHEMBL21886493 | 0.73 | ALDH1A1 (0.52) | CYP1A2ALDH1A1 | |
| SCHEMBL26048629 | 0.73 | ALDH1A1 (0.52) | CYP1A2ALDH1A1 | |
| SCHEMBL25306947 | 0.73 | CYP1A2 (0.41) | CYP1A2ALDH1A1SLC6A3 | |
| SCHEMBL11175135 | 0.72 | MEN1 (0.45) | MEN1KMT2ACYP1A2ALDH1A1PREP | |
| SCHEMBL8029828 | 0.71 | KEAP1 (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121241-A | TREATING CARDIOVASCULAR DISORDERS | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2000-09-19 | — | — | US | disclosed |
| EP-0863871-B1 | ANTICOAGULANT PEPTIDE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET (HU) | 2000-03-08 | — | — | EP | disclosed |
| EP-0863871-A1 | ANTICOAGULANT PEPTIDE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET KFT. (HU) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997046523-A1 | ANTICOAGULANT PEPTIDE ALDEHYDE DERIVATIVES | Gyógyszerkutató Intézet Kft. (HU) | 1997-12-11 | — | — | WO | disclosed |