Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17459402 | 0.77 | GABBR2 (0.41) | GABBR2GABBR1POLBALDH1A1HPGD | |
| SCHEMBL3615972 | 0.76 | GABBR2 (0.44) | GABBR2GABBR1POLBALDH1A1HPGD | |
| SCHEMBL8028596 | 0.76 | GABBR2 (0.41) | GABBR2GABBR1POLBALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL2819034 | 0.74 | GABBR2 (0.43) | GABBR2GABBR1POLBALDH1A1HPGD | |
| SCHEMBL11465688 | 0.73 | HPGD (0.40) | POLBALDH1A1HPGDGAAF2 | |
| SCHEMBL11791477 | 0.70 | GABBR2 (0.45) | GABBR2GABBR1POLBALDH1A1MAPT | |
| SCHEMBL13701476 | 0.69 | SLC6A3 (0.52) | — | |
| SCHEMBL28566434 | 0.68 | KMT2A (0.58) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL13116491 | 0.68 | TAS1R3 (0.46) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8189892 | 0.66 | POLB (0.40) | POLBALDH1A1HPGDCASP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000071785-A2 | 2-CYLCOALKYLCARBONYLCYCLOHEXANE-1,3-DIONE DERIVATIVES AS HERBICIDES | ZENECA LIMITED (GB) | 2000-11-30 | — | — | WO | disclosed |