SCHEMBL8028560

SCHEMBL8028560

COC(=O)c1ccc(OP(=O)(O)c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.55
MAPT P10636 6/20 0.54
RAB9A P51151 5/20 0.54
CA1 P00915 3/20 0.54
CA2 P00918 3/20 0.54
CA12 O43570 1/20 0.54
CA4 P22748 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.50
NPC1 O15118 3/20 0.50
PTPN1 P18031 1/20 0.50
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
POLB P06746 1/20 0.49
CASP3 P42574 1/20 0.49
SENP8 Q96LD8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21271858 0.86 L3MBTL1 (0.59) TSHRMAPTRAB9ACA1CA2
SCHEMBL20819121 0.83 CA2 (0.71) TSHRCA1CA2CA12CA4
SCHEMBL29034879 0.82 CA4 (0.61) MAPTRAB9ACA1CA2CA12
SCHEMBL4346762 0.80 TSHR (0.62) TSHRMAPTRAB9ACA1CA2
SCHEMBL21121928 0.80 CA1 (0.62) TSHRMAPTRAB9ACA1CA2
SCHEMBL9098733 0.80 CA1 (0.62) TSHRMAPTRAB9ACA1CA2
Bicarbonate SCHEMBL11410140 0.79 CA2 (0.62) TSHRCA1CA2CA12CA4
SCHEMBL752987 0.79 CA2 (0.66) TSHRCA1CA2CA12CA4
Benzene SCHEMBL28297820 0.79 CA2 (0.66) TSHRCA1CA2CA12CA4
SCHEMBL2208067 0.79 MAPT (0.52) TSHRMAPTRAB9ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1177882-C Polymerization catalyst for polyester production, polyester and process for producing polyester �����֯��ʽ���� 2004-12-01 CN disclosed
CN-1330672-A Polymerization catalyst for polyester production, polyester and process for producing polyester TOYO BOSEKI (JP) 2002-01-09 CN disclosed
US-6133404-A CONDENSATION POLYMERIZATION OF DIACID AND DIOL MONOMERS USING CATALYST MIXTURE COMPRISING COMPOUNDS OF TITANIUM, ZINC, ANTIMONY AND PHOSPHORUS TO FORM BIODEGRADABLE HIGH-MOLECULAR WEIGHT POLYESTER WITH GOOD THERMAL AND MECHANICAL PROPERTIES NATIONAL INSTITUTE OF TECHNOLOGY AND QUALITY (KR) 2000-10-17 US disclosed