Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.45 |
| ▸ | ACE | P12821 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451445 | 0.85 | MME (0.36) | MMEACECYP2D6CYP2C19 | |
| SCHEMBL8452153 | 0.80 | MME (0.46) | MMEACECA12CA1CA2 | |
| SCHEMBL8028702 | 0.79 | MME (0.61) | MMEACESMN1; SMN2CA2 | |
| SCHEMBL8028700 | 0.79 | MME (0.61) | MMEACESMN1; SMN2CA2 | |
| SCHEMBL8453835 | 0.79 | MME (0.61) | MMEACESMN1; SMN2CA2 | |
| SCHEMBL8033722 | 0.74 | MME (0.56) | MMEACESMN1; SMN2CA12CA1 | |
| SCHEMBL8033718 | 0.74 | MME (0.56) | MMEACESMN1; SMN2CA12CA1 | |
| SCHEMBL27750762 | 0.74 | CYP2D6 (0.50) | CA12CA1CA2CA9CYP2D6 | |
| SCHEMBL8030358 | 0.72 | MME (0.43) | MMEACESMN1; SMN2 | |
| SCHEMBL8030354 | 0.72 | MME (0.43) | MMEACESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |