Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1845280 | 1.00 | HTT (0.40) | HTTDGAT1KMT2ALMNACA12 | |
| SCHEMBL19407016 | 1.00 | HTT (0.40) | HTTDGAT1KMT2ALMNACA12 | |
| SCHEMBL8030378 | 1.00 | HTT (0.40) | HTTDGAT1KMT2ALMNACA12 | |
| SCHEMBL17243717 | 0.89 | HTT (0.34) | HTTDGAT1KMT2ALMNACA12 | |
| SCHEMBL6058611 | 0.89 | TSHR (0.50) | HTTDGAT1KMT2ALMNACA12 | |
| SCHEMBL18206870 | 0.89 | DGAT1 (0.44) | HTTDGAT1KMT2ALMNACA12 | |
| SCHEMBL11855010 | 0.86 | CA1 (0.39) | DGAT1KMT2ALMNACA12CA14 | |
| SCHEMBL4671957 | 0.86 | CA1 (0.39) | DGAT1KMT2ALMNACA12CA14 | |
| SCHEMBL16667110 | 0.86 | KMT2A (0.39) | HTTDGAT1KMT2ALMNACA12 | |
| SCHEMBL4671964 | 0.86 | CA1 (0.39) | DGAT1KMT2ALMNACA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9630905-B2 | Amphiphilic macromolecules and methods of use thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-04-25 | — | — | US | disclosed |
| US-9630905-B2 | Amphiphilic macromolecules and methods of use thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-04-25 | — | — | US | disclosed |
| US-20160068467-A1 | AMPHIPHILIC MACROMOLECULES AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-03-10 | — | — | US | disclosed |
| US-20160068467-A1 | AMPHIPHILIC MACROMOLECULES AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-03-10 | — | — | US | disclosed |
| WO-2000063152-A1 | ACETYLATED AND RELATED ANALOGUES OF CHICORIC ACID AS HIV INTEGRASE INHIBITORS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068467-A1 | AMPHIPHILIC MACROMOLECULES AND METHODS OF USE THEREOF | ZYX, APOB, MSR1 | HTT 1407/4885DGAT1 795/4885KMT2A 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.