SCHEMBL1845280

SCHEMBL1845280

CC(C)(C)OC(=O)C(O)C(O)C(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.40
DGAT1 O75907 1/20 0.40
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
CA12 O43570 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CYP2D6 P10635 1/20 0.34
NOS1 P29475 2/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8028869 1.00 HTT (0.40) HTTDGAT1KMT2ALMNACA12
SCHEMBL19407016 1.00 HTT (0.40) HTTDGAT1KMT2ALMNACA12
SCHEMBL8030378 1.00 HTT (0.40) HTTDGAT1KMT2ALMNACA12
SCHEMBL17243717 0.89 HTT (0.34) HTTDGAT1KMT2ALMNACA12
SCHEMBL6058611 0.89 TSHR (0.50) HTTDGAT1KMT2ALMNACA12
SCHEMBL18206870 0.89 DGAT1 (0.44) HTTDGAT1KMT2ALMNACA12
SCHEMBL11855010 0.86 CA1 (0.39) DGAT1KMT2ALMNACA12CA14
SCHEMBL4671957 0.86 CA1 (0.39) DGAT1KMT2ALMNACA12CA14
SCHEMBL16667110 0.86 KMT2A (0.39) HTTDGAT1KMT2ALMNACA12
SCHEMBL4671964 0.86 CA1 (0.39) DGAT1KMT2ALMNACA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115286510-A L-tartaric acid di-tert-butyl ester crystal form and preparation method thereof 山东药品食品职业学院 2022-11-04 CN claimed
WO-2000063152-A1 ACETYLATED AND RELATED ANALOGUES OF CHICORIC ACID AS HIV INTEGRASE INHIBITORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2000-10-26 WO claimed
CN-116917446-B Hydroprocessing process using catalyst sequences with nickel, molybdenum and tungsten based catalysts IFP Energies Nouvelles (FR) 2026-05-26 CN disclosed
US-12629669-B2 Method for rejuvenating a catalyst from a hydroprocessing and/or hydrocracking process IFP Energies Nouvelles (FR) 2026-05-19 US disclosed
EP-4558588-B1 HYDROTREATMENT PROCESS USING A SEQUENCE OF CATALYSTS WITH A CATALYST BASED ON NICKEL AND TUNGSTEN ON A SILICA-ALUMINA SUPPORT IFP ENERGIES NOW (FR) 2026-05-13 EP disclosed
US-12590254-B2 Method for hydrodesulfurisation of a petroleum fraction using a catalyst containing a graphitic material characterised by the H/C ratio thereof IFP Energies Nouvelles (FR) 2026-03-31 US disclosed
US-20260035357-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCE INC (US) 2026-02-05 US disclosed
US-12521702-B2 Trimetallic catalyst made from nickel, molybdenum and tungsten and use thereof in a hydrotreatment and/or hydrocracking process IFP Energies Nouvelles (FR) 2026-01-13 US disclosed
US-12467003-B2 Hydrotreating process using a sequence of catalyst with a catalyst based on nickel, molybdenum and tungsten IFP Energies Nouvelles (FR) 2025-11-11 US disclosed
US-12404262-B2 Therapeutic compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2025-09-02 US disclosed
EP-4558588-A1 HYDROTREATMENT PROCESS USING A SEQUENCE OF CATALYSTS WITH A CATALYST BASED ON NICKEL AND TUNGSTEN ON A SILICA-ALUMINA SUPPORT IFP Energies nouvelles (FR) 2025-05-28 EP disclosed
US-20100152463-A1 Methods for Preparing Fluoroalkyl Arylsulfinyl Compounds and Fluorinated Compounds Thereto IM&T RESEARCH, INC. (US) 2010-06-17 US disclosed
WO-2010022001-A1 METHODS FOR PREPARING FLUOROALKYL ARYLSULFINYL COMPOUNDS AND FLUORINATED COMPOUNDS THERETO IM&T RESEARCH, INC. (US) 2010-02-25 WO disclosed
US-20090082393-A1 New addition salts of angiotensin-converting enzyme inhibitors with no donor acids, a process for their preparation and pharmaceutical compositions containing them LES LABORATOIRES SERVIER (FR) 2009-03-26 US disclosed
CN-101146809-A Process for preparing quinoline compounds and products obtained therefrom WYETH CORP (US) 2008-03-19 CN disclosed
WO-2000063152-A1 ACETYLATED AND RELATED ANALOGUES OF CHICORIC ACID AS HIV INTEGRASE INHIBITORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2000-10-26 WO disclosed
EP-0094815-B1 OLIGOPEPTIDE PRODRUGS SMITHKLINE BECKMAN CORPORATION (US) 1989-01-11 EP disclosed
US-4479898-A Oligopeptide prodrugs SMITHKLINE BECKMAN CORPORATION (US) 1984-10-30 US disclosed
US-4454065-A INCREASE CELL MEMBRANE PERMEABILITY SMITHKLINE BECKMAN CORPORATION (US) 1984-06-12 US disclosed
EP-0094815-A2 Oligopeptide prodrugs SMITHKLINE BECKMAN CORPORATION (US) 1983-11-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152463-A1 Methods for Preparing Fluoroalkyl Arylsulfinyl Compounds and Fluorinated Compounds Thereto PFAS, AGPS, FDPS HTT 2771/4885DGAT1 870/4885KMT2A 3317/4885
US-12590254-B2 Method for hydrodesulfurisation of a petroleum fraction using a catalyst containing a graphitic material characterised by the H/C ratio thereof HMOX2, SCO2, HAO2 HTT 1589/4885DGAT1 582/4885KMT2A 3494/4885
US-12404262-B2 Therapeutic compounds for HIV virus infection HAVCR2, MAVS, CD4 HTT 3181/4885DGAT1 1401/4885KMT2A 3782/4885
US-12629669-B2 Method for rejuvenating a catalyst from a hydroprocessing and/or hydrocracking process HOGA1, GK, PCK2 HTT 177/4885DGAT1 1058/4885KMT2A 2571/4885
US-20090082393-A1 New addition salts of angiotensin-converting enzyme inhibitors with no donor acids, a process for their preparation and pharmaceutical compositions containing them ACE, AGTR1, AGT HTT 4634/4885DGAT1 2576/4885KMT2A 3071/4885
US-20260035357-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION CCR10, CCR1, CCR3 HTT 4711/4885DGAT1 1321/4885KMT2A 4244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.