Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.57 |
| ▸ | MME | P08473 | 11/20 | 0.57 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027428 | 0.91 | ACE (0.47) | ACEMMEPPARGPPARAMEN1 | |
| SCHEMBL8027312 | 0.88 | ACE (0.61) | ACEMMEPPARGPPARAMEN1 | |
| SCHEMBL8028951 | 0.88 | ACE (0.58) | ACEMMEPPARGPPARAMEN1 | |
| SCHEMBL8027420 | 0.87 | MME (0.77) | ACEMMEPPARGPPARAMEN1 | |
| SCHEMBL8027314 | 0.87 | MME (0.72) | ACEMMEACE2CPA1 | |
| SCHEMBL8027310 | 0.87 | MME (0.72) | ACEMMEACE2CPA1 | |
| SCHEMBL27543291 | 0.85 | PPARG (0.45) | ACEMMEPPARGPPARA | |
| SCHEMBL8032846 | 0.84 | ACE (0.74) | ACEMMEMEN1KMT2AACE2 | |
| SCHEMBL8027141 | 0.83 | MME (0.63) | ACEMMEACE2CPA1 | |
| SCHEMBL8033727 | 0.83 | MME (0.62) | ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |