SCHEMBL1807043

SCHEMBL1807043

COc1ccc(OCCC(=O)O)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.72
MAPT P10636 3/20 0.68
FFAR1 O14842 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.59
MEN1 O00255 1/20 0.59
NPC1 O15118 1/20 0.59
ALDH1A1 P00352 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
RAB9A P51151 1/20 0.59
KMT2A Q03164 1/20 0.59
TSHR P16473 1/20 0.58
LMNA P02545 2/20 0.58
MMP2 P08253 1/20 0.57
HPGD P15428 1/20 0.57
MTNR1A P48039 1/20 0.56
MTNR1B P49286 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anisole SCHEMBL28094109 0.92 MAPT (0.65) L3MBTL1MAPTFFAR1SMN1; SMN2MEN1
SCHEMBL8029095 0.90 PDE4B (0.64) L3MBTL1MAPTFFAR1SMN1; SMN2MEN1
Hydrochloric Acid SCHEMBL8981950 0.89 PDE4B (0.62) L3MBTL1MAPTFFAR1SMN1; SMN2MEN1
SCHEMBL15176983 0.89 PPARA (0.65) L3MBTL1MAPTFFAR1MTNR1AMTNR1B
SCHEMBL1801957 0.87 PPARA (0.68) L3MBTL1MAPTFFAR1ALDH1A1PDE4B
SCHEMBL8483507 0.87 PPARA (0.68) L3MBTL1MAPTFFAR1ALDH1A1PDE4B
SCHEMBL4298103 0.87 PPARA (0.68) L3MBTL1MAPTFFAR1ALDH1A1PDE4B
SCHEMBL9559951 0.85 CYP1A2 (0.62) L3MBTL1MAPTFFAR1SMN1; SMN2NPC1
SCHEMBL1806524 0.84 L3MBTL1 (1.00) L3MBTL1FFAR1MEN1NPC1ALDH1A1
SCHEMBL22578056 0.84 MCL1 (0.61) L3MBTL1MAPTFFAR1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6682766-B2 FULL FLAVOR THE PROCTER & GAMBLE COMPANY 2004-01-27 US claimed
EP-1041898-B1 BEVERAGE COMPRISING AN EFFECTIVE AMOUNT OF A SWEETNESS CUTTING COMPOSITION PROCTER & GAMBLE (US) 2003-05-02 EP claimed
EP-1041898-A1 BEVERAGE COMPRISING AN EFFECTIVE AMOUNT OF A SWEETNESS CUTTING COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2000-10-11 EP claimed
WO-1999027804-A1 BEVERAGE COMPRISING AN EFFECTIVE AMOUNT OF A SWEETNESS CUTTING COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1999-06-10 WO claimed
US-5631038-A COMPOUNDS (TASTANDS) TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE ARE ADDED TO FOODS CONTAINING SODIUM CHLORIDE BIORESEARCH, INC. (US) 1997-05-20 US claimed
EP-0661932-A4 SPECIFIC EATABLE TASTE MODIFIERS. BIORESEARCH INC (US) 1996-06-05 EP claimed
EP-0661932-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1995-07-12 EP claimed
WO-1993010677-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1993-06-10 WO claimed
EP-4626865-A1 CYCLIC PYRAZOLE DIAMIDE IRE1/XBP1S ACTIVATORS Protego Biopharma, Inc. (US) 2025-10-08 EP disclosed
WO-2024118810-A1 CYCLIC PYRAZOLE DIAMIDE IRE1/XBP1S ACTIVATORS PROTEGO BIOPHARMA, INC. (US) 2024-06-06 WO disclosed
US-11858876-B2 CCL2 inhibitors LAPKO INC. (US) 2024-01-02 US disclosed
US-20220409566-A1 CCL5 Inhibitors LAPKO INC, dba AFECTA PHARMACEUTICALS 2022-12-29 US disclosed
US-20220142961-A1 CCL5 Inhibitors LAPKO INC, dba AFECTA PHARMACEUTICALS 2022-05-12 US disclosed
US-11318111-B2 CCL5 inhibitors LAPKO INC (US) 2022-05-03 US disclosed
US-5059609-A Lipoxygenase inhibitors; leukotriene receptor blockers; psoriasis; antiulcer agents and myocardial infarctions PFIZER INC. (US) 1991-10-22 US disclosed
WO-1990012010-A1 SUBSTITUTED CHROMANS IN THE TREATMENT OF ASTHMA, ARTHRITIS AND RELATED DISEASES PFIZER INC. (US) 1990-10-18 WO disclosed
EP-0391625-A1 Substituted chromans in the treatment of asthma, arthritis and related diseases PFIZER INC. (US) 1990-10-10 EP disclosed
WO-1989003681-A1 SUBSTITUTED TETRALINS, CHROMANS AND RELATED COMPOUNDS IN THE TREATMENT OF ASTHMA PFIZER INC. (US) 1989-05-05 WO disclosed
EP-0313296-A2 Substituted chromans and related compounds in the treatment of asthma PFIZER INC. (US) 1989-04-26 EP disclosed
EP-0313295-A2 Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases PFIZER INC. (US) 1989-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220142961-A1 CCL5 Inhibitors CCL5, CCL11, CCR5 L3MBTL1 1170/4885MAPT 4264/4885FFAR1 147/4885
US-11318111-B2 CCL5 inhibitors CCL5, CCL11, CCR5 L3MBTL1 1170/4885MAPT 4264/4885FFAR1 147/4885
US-20220409566-A1 CCL5 Inhibitors CCL5, CCL11, CCR5 L3MBTL1 1170/4885MAPT 4264/4885FFAR1 147/4885
US-11858876-B2 CCL2 inhibitors CCL2, CCL11, CCR2 L3MBTL1 2730/4885MAPT 1328/4885FFAR1 1624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.