SCHEMBL8029546

SCHEMBL8029546

CCOC(=O)/C=C(/C)NC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
GAA P10253 2/20 0.43
POLB P06746 2/20 0.43
HTT P42858 2/20 0.42
RECQL P46063 2/20 0.41
MAPT P10636 1/20 0.41
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HSD17B10 Q99714 1/20 0.39
GLA P06280 1/20 0.39
USP2 O75604 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7707528 0.84 NAAA (0.41) MEN1KMT2AALDH1A1NPSR1GAA
SCHEMBL10690004 0.80 RECQL (0.47) MEN1KMT2AALDH1A1GAAPOLB
SCHEMBL2082055 0.80 NPSR1 (0.44) MEN1KMT2AALDH1A1NPSR1GAA
SCHEMBL2082056 0.80 NPSR1 (0.44) MEN1KMT2AALDH1A1NPSR1GAA
SCHEMBL8029766 0.80 RECQL (0.47) MEN1KMT2AALDH1A1GAAPOLB
SCHEMBL10991852 0.79 KMT2A (0.52) MEN1KMT2AALDH1A1NPSR1GAA
SCHEMBL8779022 0.79 POLB (0.47) KMT2AALDH1A1GAAPOLBHTT
SCHEMBL7707671 0.79 POLB (0.47) KMT2AALDH1A1GAAPOLBHTT
SCHEMBL1242807 0.77 LMNA (0.43) ALDH1A1NPSR1GAAHTTMAPT
SCHEMBL1242806 0.77 LMNA (0.43) ALDH1A1NPSR1GAAHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0983240-A1 LIGHT-STABILIZED ORGANIC POLYMERS Great Lakes Chemical (Europe) GmbH (CH) 2000-03-08 EP disclosed
WO-1998050360-A1 LIGHT-STABILIZED ORGANIC POLYMERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 1998-11-12 WO disclosed