Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405569 | 0.75 | ESR2 (0.50) | SLC18A3LMNARAB9AHTTALDH1A1 | |
| SCHEMBL17045230 | 0.74 | SLC18A3 (0.38) | SLC18A3LMNARAB9AHTTALDH1A1 | |
| SCHEMBL16892913 | 0.72 | ESR2 (0.50) | SLC18A3LMNAALDH1A1MAPTESR2 | |
| SCHEMBL12841058 | 0.72 | SLC18A3 (0.42) | SLC18A3LMNARAB9AHTTALDH1A1 | |
| SCHEMBL734536 | 0.71 | MAOB (0.42) | SLC18A3LMNAALDH1A1MAPTESR2 | |
| SCHEMBL13476556 | 0.71 | MAOB (0.42) | SLC18A3LMNAALDH1A1MAPTESR2 | |
| Methyl Alcohol SCHEMBL8600293 | 0.71 | SLC18A3 (0.41) | SLC18A3LMNARAB9AHTTALDH1A1 | |
| SCHEMBL12463654 | 0.71 | MAOB (0.42) | SLC18A3LMNAALDH1A1MAPTESR2 | |
| SCHEMBL10212287 | 0.70 | SLC18A3 (0.43) | SLC18A3LMNAALDH1A1MAPTESR2 | |
| SCHEMBL10062044 | 0.70 | ESR2 (0.65) | SLC18A3LMNARAB9AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000076316-A1 | METHODS RELATED TO METABOLISM OF PARASITES AND MYCOBACTERIA | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2000-12-21 | — | — | WO | disclosed |