Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.65 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428038 | 0.94 | ESR2 (0.59) | ESR2SLC18A3RAB9AHTTALDH1A1 | |
| SCHEMBL172111 | 0.94 | ESR2 (0.59) | ESR2SLC18A3RAB9AHTTALDH1A1 | |
| SCHEMBL1405569 | 0.88 | ESR2 (0.50) | ESR2SLC18A3RAB9AHTTALDH1A1 | |
| Bicarbonate SCHEMBL1720129 | 0.82 | NPC1 (0.48) | ESR2SLC18A3RAB9AALDH1A1CYP3A4 | |
| SCHEMBL12675264 | 0.82 | ESR2 (0.69) | ESR2CYP3A4CYP2C9ESR1 | |
| SCHEMBL14173678 | 0.79 | ESR2 (0.43) | ESR2SLC18A3CYP3A4CYP2C9 | |
| SCHEMBL24597681 | 0.79 | ESR2 (0.65) | ESR2SLC18A3RAB9AHTTALDH1A1 | |
| SCHEMBL605342 | 0.79 | ESR2 (1.00) | ESR2CYP3A4CYP2C9ESR1 | |
| SCHEMBL19937427 | 0.79 | ESR2 (0.65) | ESR2SLC18A3RAB9AHTTALDH1A1 | |
| SCHEMBL19294268 | 0.79 | SLC18A3 (0.44) | ESR2SLC18A3RAB9AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043782-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| EP-3980510-B1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2023-11-08 | — | — | EP | disclosed |
| US-11788009-B2 | Liquid-crystalline medium for use in a switching element | MERCK PATENT GMBH (DE) | 2023-10-17 | — | — | US | disclosed |
| US-11762241-B2 | Device for the regulation of light transmission | MERCK PATENT GMBH (DE) | 2023-09-19 | — | — | US | disclosed |
| US-11760931-B2 | Liquid-crystalline medium for use in a switching element | MERCK PATENT GMBH (DE) | 2023-09-19 | — | — | US | disclosed |
| US-11702597-B2 | Azo dye | MERCK PATENT GMBH (DE) | 2023-07-18 | — | — | US | disclosed |
| US-11667840-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2023-06-06 | — | — | US | disclosed |
| US-11667845-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2023-06-06 | — | — | US | disclosed |
| US-20230068853-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2023-03-02 | — | — | US | disclosed |
| US-20230056437-A1 | AZO DYE | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| EP-1932896-B1 | Stilbene derivatives, liquid-crystal mixtures and electro-optical displays | MERCK PATENT GMBH (DE) | 2010-10-27 | — | — | EP | disclosed |
| WO-2010089092-A1 | LIQUID CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2010-08-12 | — | — | WO | disclosed |
| US-7732022-B2 | Stilbene derivatives, liquid-crystal mixtures and electro-optical displays | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-06-08 | — | — | US | disclosed |
| EP-2100944-A1 | Liquid crystal medium and liquid crystal display | MERCK PATENT GmbH (DE) | 2009-09-16 | — | — | EP | disclosed |
| US-20090213318-A1 | Liquid crystal medium and electrooptical display containing same | MERCK PATENT GESELLSCHAFT (DE) | 2009-08-27 | — | — | US | disclosed |
| WO-2008138456-A1 | MODULATION ELEMENTS FOR ELECTROMAGNETIC RADIATION, MODULATION DEVICE AND MODULATION MEDIUM | MERCK PATENT GMBH (DE) | 2008-11-20 | — | — | WO | disclosed |
| US-20080149891-A1 | STILBENE DERIVATIVES, LIQUID-CRYSTAL MIXTURES AND ELECTRO-OPTICAL DISPLAYS | MERCK PATENT GESELLSCHAFT (DE) | 2008-06-26 | — | — | US | disclosed |
| WO-2007017008-A1 | ELECTRO-OPTICAL LIGHT MODULATION ELEMENT, DISPLAY AND MEDIUM | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | WO | disclosed |
| US-4187152-A | Extractive distillation for separating ketones and/or alcohols from phenol and/or cresol | ALLIED CHEMICAL CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
| US-3960961-A | 4'-Fluoro-4-{[4-(phenyl)cyclohexyl]amino}butyrophenones and the salts thereof | THE UPJOHN COMPANY (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667845-B2 | Liquid crystalline medium | NEFM, CCNI, MYT1 | ESR2 2503/4885SLC18A3 1269/4885RAB9A 4738/4885 |
| US-20230068853-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | CXCR1, PYM1, F11 | ESR2 2704/4885SLC18A3 4212/4885RAB9A 3183/4885 |
| US-20080149891-A1 | STILBENE DERIVATIVES, LIQUID-CRYSTAL MIXTURES AND ELECTRO-OPTICAL DISPLAYS | SBDS, LSS, VCL | ESR2 1012/4885SLC18A3 925/4885RAB9A 1076/4885 |
| US-11667840-B2 | Liquid-crystalline medium | FES, BLM, CXCL12 | ESR2 3456/4885SLC18A3 2741/4885RAB9A 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.