Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HLCS | P50747 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029695 | 0.79 | MMP1 (0.38) | MMP1MMP3MMP9PRKCDALDH1A1 | |
| SCHEMBL19683169 | 0.70 | ALDH1A1 (0.37) | PRKCDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11864710 | 0.70 | ALDH1A1 (0.37) | PRKCDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL221917 | 0.67 | GBA1 (0.41) | MMP1MMP3MMP9PRKCDALDH1A1 | |
| SCHEMBL8607884 | 0.67 | CYP1A2 (0.31) | — | |
| SCHEMBL5452034 | 0.66 | — | — | |
| SCHEMBL10714123 | 0.66 | PRKCD (0.42) | PRKCDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8029726 | 0.66 | ALDH1A1 (0.33) | MMP1MMP3MMP9ALDH1A1HLCS | |
| SCHEMBL8998181 | 0.65 | ALDH1A1 (0.45) | MMP1MMP3MMP9ALDH1A1MEN1 | |
| SCHEMBL5442521 | 0.65 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3072774-B2 | — | — | 2000-08-07 | — | — | JP | claimed |
| EP-0513239-B1 | N,N'-DIHALOIMIDAZOLIDIN-4-ONES | UNIV AUBURN (US) | 1998-04-08 | — | — | EP | claimed |
| EP-0513239-A4 | N,N'-DIHALOIMIDAZOLIDIN-4-ONES | — | 1993-03-10 | — | — | EP | claimed |
| EP-0513239-A1 | N,N'-DIHALOIMIDAZOLIDIN-4-ONES | AUBURN UNIVERSITY (US) | 1992-11-19 | — | — | EP | claimed |
| US-5126057-A | Stabilizers against solar radiation | AUBURN RESEARCH FOUNDATION (US) | 1992-06-30 | — | — | US | claimed |
| WO-1991010623-A1 | N,N'-DIHALOIMIDAZOLIDIN-4-ONES | AUBURN UNIVERSITY (US) | 1991-07-25 | — | — | WO | claimed |