Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7426888 | 0.90 | GAA (0.37) | MAPTGAAADRA2CACHEF2 | |
| Trifluoroacetic Acid SCHEMBL5212475 | 0.90 | GAA (0.37) | MAPTGAAADRA2CACHEF2 | |
| SCHEMBL30900484 | 0.73 | GAA (0.71) | MAPTGAAF2 | |
| SCHEMBL10742930 | 0.73 | GAA (0.71) | MAPTGAAF2 | |
| SCHEMBL2266601 | 0.73 | GAA (0.71) | MAPTGAAF2 | |
| Hydrochloric Acid SCHEMBL28262901 | 0.72 | GAA (0.69) | MAPTGAAF2 | |
| SCHEMBL698882 | 0.71 | ADRA2C (0.64) | GAAADRA2CMLYCDRORCALDH1A1 | |
| SCHEMBL6174036 | 0.65 | ADRA2C (0.51) | MAPTADRA2CMLYCDACHEHPGD | |
| SCHEMBL10349935 | 0.65 | MEN1 (0.56) | MAPTADRA2CRORCACHEALDH1A1 | |
| SCHEMBL9716701 | 0.65 | ADRA2C (0.55) | MAPTADRA2CMLYCDALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000077027-A2 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2000-12-21 | — | — | WO | disclosed |