Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029881 | 0.91 | KCNJ1 (0.46) | ALDH1A1PKMLMNAKMT2AMEN1 | |
| SCHEMBL6159759 | 0.90 | KMT2A (0.58) | ALDH1A1PKMLMNAKMT2AMEN1 | |
| SCHEMBL7981313 | 0.86 | ALDH1A1 (0.44) | ALDH1A1PKMLMNAKMT2AMEN1 | |
| SCHEMBL16590350 | 0.85 | ALDH1A1 (0.58) | ALDH1A1PKMLMNAKMT2AMEN1 | |
| SCHEMBL590346 | 0.84 | PKM (0.61) | ALDH1A1PKMLMNAKMT2AMEN1 | |
| SCHEMBL7377767 | 0.84 | ALDH1A1 (0.53) | ALDH1A1PKMLMNAKMT2AMEN1 | |
| SCHEMBL12217716 | 0.80 | ALDH1A1 (0.60) | ALDH1A1PKMLMNAKMT2AMEN1 | |
| SCHEMBL8028137 | 0.80 | CNR2 (0.48) | KMT2ACNR2SMN1; SMN2 | |
| SCHEMBL8032940 | 0.79 | KCNJ1 (0.48) | ALDH1A1LMNAKMT2AMEN1CNR2 | |
| SCHEMBL8026313 | 0.78 | ABCG2 (0.50) | ALDH1A1PKMLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |