Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637649 | 0.89 | KCNJ1 (0.53) | KCNJ1KCNH2CYP19A1MAPTALDH1A1 | |
| SCHEMBL8029974 | 0.79 | ALDH1A1 (0.55) | KCNJ1KCNH2MAPTALDH1A1MEN1 | |
| SCHEMBL8016775 | 0.79 | BRPF1 (0.41) | KCNJ1KCNH2KMT2AIDH1RORC | |
| SCHEMBL8029881 | 0.77 | KCNJ1 (0.46) | KCNJ1KCNH2CYP19A1MAPTALDH1A1 | |
| SCHEMBL8030047 | 0.77 | KMT2A (0.46) | KMT2AIDH1 | |
| SCHEMBL7981313 | 0.77 | ALDH1A1 (0.44) | KCNJ1KCNH2MAPTALDH1A1GAA | |
| SCHEMBL6230356 | 0.75 | CYP19A1 (0.59) | CYP19A1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL6232857 | 0.75 | CYP19A1 (0.56) | CYP19A1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL7360923 | 0.74 | KCNJ1 (0.52) | KCNJ1KCNH2CYP19A1RORC | |
| SCHEMBL6159759 | 0.74 | KMT2A (0.58) | KCNJ1KCNH2CYP19A1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |