Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409593 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1GRIA4DAO | |
| SCHEMBL5992486 | 0.80 | TAAR1 (0.56) | ALDH1A1MAPTL3MBTL1MAOBGRIA4 | |
| SCHEMBL27652849 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1MAOBGRIA4 | |
| SCHEMBL28880915 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1GRIA4DAO | |
| SCHEMBL10436028 | 0.78 | MAOB (0.65) | ALDH1A1MAPTL3MBTL1MAOBGRIA4 | |
| SCHEMBL21235252 | 0.75 | MAOB (0.51) | ALDH1A1MAPTL3MBTL1MAOBGRIA4 | |
| SCHEMBL30920080 | 0.75 | MAOB (0.51) | ALDH1A1MAPTL3MBTL1MAOBGRIA4 | |
| SCHEMBL12856701 | 0.74 | PTPRC (0.56) | ALDH1A1MAPTL3MBTL1GRIA4PPARG | |
| SCHEMBL16056409 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1GRIA4DAO | |
| SCHEMBL11452249 | 0.73 | LOXL2 (0.54) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006156-A1 | AMIDE, CARBAMATE, AND UREA DERIVATIVES | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |