Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 9/20 | 0.85 |
| ▸ | HTR6 | P50406 | 7/20 | 0.81 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029215 | 0.92 | RXFP1 (0.82) | RXFP1HTR6THRBMAPTPOLB | |
| SCHEMBL8018275 | 0.91 | RXFP1 (0.82) | RXFP1HTR6THRBMAPTPOLB | |
| SCHEMBL8028230 | 0.90 | HTR6 (0.98) | RXFP1HTR6THRBTP53 | |
| SCHEMBL8019326 | 0.88 | HTR6 (0.98) | RXFP1HTR6THRBMAPTPOLB | |
| SCHEMBL8030175 | 0.86 | RXFP1 (0.78) | RXFP1HTR6THRBMAPTPOLB | |
| SCHEMBL8026952 | 0.85 | RXFP1 (0.76) | RXFP1HTR6THRBPOLB | |
| SCHEMBL8019324 | 0.82 | RXFP1 (1.00) | RXFP1HTR6THRBMAPTTP53 | |
| SCHEMBL8017003 | 0.82 | THRB (0.84) | RXFP1HTR6THRBMAPT | |
| SCHEMBL8026961 | 0.81 | RXFP1 (1.00) | RXFP1HTR6THRBMAPTTP53 | |
| SCHEMBL8027278 | 0.81 | HTR6 (0.85) | RXFP1HTR6THRBMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093934-A2 | SUBSTITUTED 3-SULPHONYL-[1,2,3]TRIAZOLO [1,5-A]PYRIMIDINES-ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, MEDICINAL SUBSTANCE, PHARMACEUTICAL COMPOSITION, MEDICINAL PREPARATION AND METHODS FOR THE PRODUCTION THEREOF | ALLA CHEM, LLC (US) | 2009-07-30 | — | — | WO | disclosed |