Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.81 |
| ▸ | MAOA | P21397 | 1/20 | 0.77 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986745 | 1.00 | CHRM2 (0.81) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL8034858 | 1.00 | CHRM2 (0.81) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL8029033 | 0.98 | CHRM2 (0.78) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL8032640 | 0.98 | CHRM2 (0.78) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL7982481 | 0.98 | MAOA (0.80) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL7984635 | 0.98 | MAOA (0.80) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL8911797 | 0.98 | MAOA (0.80) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL8034873 | 0.96 | CHRM2 (0.81) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL1040171 | 0.96 | MAOA (0.76) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL8029046 | 0.94 | CHRM2 (0.77) | CHRM2MAOASIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-B1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON SPA (IT) | 2000-03-15 | — | — | EP | disclosed |
| US-5847092-A | Erythromycin A 9-0 oxime derivatives endowed with antibiotic activity | ZAMBON GROUP S.P.A. (IT) | 1998-12-08 | — | — | US | disclosed |
| EP-0797579-A1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018633-A1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1996-06-20 | — | — | WO | disclosed |