Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.80 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.77 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.60 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982481 | 1.00 | MAOA (0.80) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL7984635 | 1.00 | MAOA (0.80) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL7986745 | 0.98 | CHRM2 (0.81) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8030792 | 0.98 | CHRM2 (0.81) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8034858 | 0.98 | CHRM2 (0.81) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL1040171 | 0.98 | MAOA (0.76) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8029033 | 0.96 | CHRM2 (0.78) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8032640 | 0.96 | CHRM2 (0.78) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8034873 | 0.94 | CHRM2 (0.81) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8029046 | 0.92 | CHRM2 (0.77) | MAOACHRM2SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048705-A1 | POTASSIUM CHANNEL BLOCKERS | UNIVERSITY COLLEGE LONDON (GB) | 1997-12-24 | — | — | WO | disclosed |