SCHEMBL7984635

SCHEMBL7984635

OCCCCCNCc1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.80
CHRM2 P08172 1/20 0.77
SIGMAR1 Q99720 5/20 0.69
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
TDP1 Q9NUW8 1/20 0.61
HDAC3 O15379 2/20 0.60
HDAC1 Q13547 2/20 0.60
HDAC2 Q92769 2/20 0.60
HDAC8 Q9BY41 2/20 0.60
NCOR2 Q9Y618 2/20 0.60
MPO P05164 1/20 0.54
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
ACHE P22303 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7982481 1.00 MAOA (0.80) MAOACHRM2SIGMAR1MEN1KMT2A
SCHEMBL8911797 1.00 MAOA (0.80) MAOACHRM2SIGMAR1MEN1KMT2A
SCHEMBL7986745 0.98 CHRM2 (0.81) MAOACHRM2SIGMAR1MEN1KMT2A
SCHEMBL8030792 0.98 CHRM2 (0.81) MAOACHRM2SIGMAR1MEN1KMT2A
SCHEMBL8034858 0.98 CHRM2 (0.81) MAOACHRM2SIGMAR1MEN1KMT2A
SCHEMBL1040171 0.98 MAOA (0.76) MAOACHRM2SIGMAR1MEN1KMT2A
SCHEMBL8029033 0.96 CHRM2 (0.78) MAOACHRM2SIGMAR1MEN1KMT2A
SCHEMBL8032640 0.96 CHRM2 (0.78) MAOACHRM2SIGMAR1MEN1KMT2A
SCHEMBL8034873 0.94 CHRM2 (0.81) MAOACHRM2SIGMAR1MEN1KMT2A
SCHEMBL8029046 0.92 CHRM2 (0.77) MAOACHRM2SIGMAR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103890088-B Resin composition AJINOMOTO CO.,INC. (JP) 2016-05-18 CN claimed
CN-111378181-A Force-induced responsive polymer with single-hybrid network structure 翁秋梅 2020-07-07 CN disclosed
US-20140234364-A1 TOTAL SYNTHESIS AND IMMUNOLOGICAL EVALUATION OF SACCHARIDE MOIETIES OF THE LIPOPOLYSACCHARIDE FROM NEISSERIA MENINGITIDIS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2014-08-21 US disclosed
CN-103890088-A Resin composition AJINOMOTO KK 2014-06-25 CN disclosed
WO-2013041732-A1 TOTAL SYNTHESIS AND IMMUNOLOGICAL EVALUATION OF SACCHARIDE MOIETIES OF THE LIPOPOLYSACCHARIDE FROM NEISSERIA MENINGITIDIS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2013-03-28 WO disclosed
EP-2573100-A1 Total synthesis of the core tetrasaccharide of the lipopolysaccharide from Neisseria meningitidis Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2013-03-27 EP disclosed
US-6214833-B1 MADE BY ACYLATION ZAMBON GROUP S.P.A. (IT) 2001-04-10 US disclosed
EP-0970075-A1 PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY ZAMBON GROUP S.p.A. (IT) 2000-01-12 EP disclosed
WO-1998043972-A1 PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY ZAMBON GROUP S.P.A. (IT) 1998-10-08 WO disclosed
WO-1997048705-A1 POTASSIUM CHANNEL BLOCKERS UNIVERSITY COLLEGE LONDON (GB) 1997-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140234364-A1 TOTAL SYNTHESIS AND IMMUNOLOGICAL EVALUATION OF SACCHARIDE MOIETIES OF THE LIPOPOLYSACCHARIDE FROM NEISSERIA MENINGITIDIS FUT5, DAD1, STT3B MAOA 2347/4885CHRM2 3598/4885SIGMAR1 1857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.