Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 6/20 | 0.41 |
| ▸ | FEN1 | P39748 | 6/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA6 | P23280 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442129 | 0.78 | LRRK2 (0.49) | ALOX5APFEN1CA1CA2CA9 | |
| SCHEMBL1990221 | 0.78 | LRRK2 (0.49) | ALOX5APFEN1CA1CA2CA9 | |
| SCHEMBL8029103 | 0.77 | FEN1 (0.50) | ALOX5APFEN1CA9CA12 | |
| SCHEMBL8350056 | 0.74 | CA1 (0.54) | ALOX5APFEN1CA1CA2CA9 | |
| SCHEMBL16177854 | 0.73 | ALOX5AP (0.48) | ALOX5APFEN1CA1CA2CA9 | |
| SCHEMBL48885 | 0.73 | CA2 (0.52) | ALOX5APFEN1CA1CA2CA9 | |
| SCHEMBL1080972 | 0.72 | CA2 (0.61) | ALOX5APFEN1CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL6399557 | 0.71 | CA2 (0.50) | ALOX5APFEN1CA1CA2CA9 | |
| Methane SCHEMBL27503773 | 0.71 | CA2 (0.50) | ALOX5APFEN1CA1CA2CA9 | |
| SCHEMBL7368182 | 0.71 | ALOX5AP (0.56) | ALOX5APFEN1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |