SCHEMBL8031111

SCHEMBL8031111

CN1C(=O)NC[C@@H]1C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.31
PIK3C3 Q8NEB9 1/20 0.31
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20956911 0.80 P2RX7 (0.33) KMT2APIK3C3P2RX7
SCHEMBL18576512 0.76 PIK3C3 (0.30) PIK3C3
SCHEMBL18389126 0.72
SCHEMBL20672077 0.72
SCHEMBL18576510 0.72
SCHEMBL21482019 0.72 P2RX7 (0.33) P2RX7
SCHEMBL3044 0.69
SCHEMBL13574954 0.69
SCHEMBL5728688 0.67
SCHEMBL22304255 0.67 LMNA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0854857-B1 METHOD OF PREPARING OPTICALLY ACTIVE ALPHA-AMINO ACIDS AND ALPHA-AMINO ACID DERIVATIVES DEGUSSA (DE) 2000-03-08 EP disclosed
US-6018050-A ENANTIOMERICALLY PURE COMPOUNDS OBTAINED IN HIGH YIELDS; PREPARING STERICALLY DEMANDING AMINO ACIDS AND THEIR DERIVATIVES, SUCH AS THE PREPARATION OF CIS-4-HYDROXYPROLINE PRECURSORS; ASYMMETRIC SYNTHESIS DEGUSSA AKTIENGESELLSCHAFT (DE) 2000-01-25 US disclosed