SCHEMBL22304255

SCHEMBL22304255

CC(C)(C)C1CNC(=O)CN1C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18576512 0.69 PIK3C3 (0.30)
SCHEMBL18896069 0.69 LMNA (0.33) LMNAMAPT
SCHEMBL22813222 0.67
SCHEMBL8031111 0.67 KMT2A (0.31)
SCHEMBL24322549 0.65 LMNA (0.37) LMNAMAPT
SCHEMBL24246510 0.65 BRD4 (0.32) LMNAMAPT
SCHEMBL14660278 0.65 CRBN (0.34) LMNAMAPT
SCHEMBL19749751 0.64 LMNA (0.32) LMNAMAPT
SCHEMBL21482019 0.63 P2RX7 (0.33)
SCHEMBL20672077 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11247993-B2 Pyridone derivative, composition and use as antiviral drug thereof JIANGXI CAISHI PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2022-02-15 US disclosed
EP-3753936-A1 PYRIDONE DERIVATIVE, COMPOSITION THEREOF AND APPLICATION THEREOF AS ANTI-INFLUENZA DRUG Jiangxi Caishi Pharmaceutical Technology Co., Ltd. (CN) 2020-12-23 EP disclosed
US-20200247812-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE INTEGRAL BIOSCIENCES PRIVATE LTD (IN) 2020-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11247993-B2 Pyridone derivative, composition and use as antiviral drug thereof PNP, POLB, POLA1 LMNA 177/4885MAPT 3679/4885
US-20200247812-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE ACVR1, ACVRL1, ALK LMNA 1500/4885MAPT 3483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.