SCHEMBL8022013

SCHEMBL8022013

CSc1c(C)c(-c2cc(O)c(Cl)cc2F)nn1C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.32
RORC P51449 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8035641 0.82 HSP90AA1 (0.34)
SCHEMBL8021924 0.80 GAA (0.36) POLBRORC
SCHEMBL8031860 0.78 HSD11B1 (0.40)
SCHEMBL7687809 0.78 AR (0.33) RORC
SCHEMBL6280477 0.77
SCHEMBL8031377 0.76 PGK1 (0.38)
SCHEMBL8624020 0.75 POLB (0.34) POLB
SCHEMBL8021916 0.75 DRD2 (0.32)
SCHEMBL7615238 0.73 MEN1 (0.36) RORC
SCHEMBL27814912 0.73 GAA (0.34) RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6103667-A Phenylpyrazole herbicides NOVARTIS CORPORATION (US) 2000-08-15 US disclosed
EP-0832070-A1 NOVEL HERBICIDES Novartis AG (CH) 1998-04-01 EP disclosed
WO-1997000246-A1 NOVEL HERBICIDES NOVARTIS AG (CH) 1997-01-03 WO disclosed