SCHEMBL9864465

SCHEMBL9864465

Cn1nc(-c2ccc(Cl)cc2Cl)c(Cl)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.50
CRHR1 P34998 8/20 0.45
AHR P35869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14996580 0.85 HSD11B1 (0.53) HSD11B1CRHR1
SCHEMBL12859389 0.81 HSD11B1 (0.45) HSD11B1CRHR1AHR
SCHEMBL15331050 0.80 HSD11B1 (0.44) HSD11B1CRHR1
SCHEMBL17290439 0.79 HSD11B1 (0.50) HSD11B1CRHR1
SCHEMBL8031277 0.76 HSD11B1 (0.47) HSD11B1CRHR1
SCHEMBL8031897 0.74 HSD11B1 (0.45) HSD11B1CRHR1
SCHEMBL8174352 0.72 HSD11B1 (0.44) HSD11B1CRHR1
SCHEMBL14996667 0.71 HSD11B1 (0.53) HSD11B1CRHR1
SCHEMBL14996575 0.71 HSD11B1 (0.53) HSD11B1CRHR1
SCHEMBL6835004 0.71 HSD11B1 (0.49) HSD11B1CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3093774-A None JP disclosed
JP-2300173-A None JP disclosed
JP-H0393774-A 3-OR 5-PHENYLPYRAZOLE COMPOUND OR ITS SALT AND HERBICIDE NIPPON NOHYAKU CO LTD 1991-04-18 JP disclosed
JP-H02300173-A 3 OR 5-PHENYLPYRAZOLES OR SALTS THEREOF AND HERBICIDE NIPPON NOHYAKU CO LTD 1990-12-12 JP disclosed