Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | RARB | P10826 | 12/20 | 0.39 |
| ▸ | RARG | P13631 | 10/20 | 0.39 |
| ▸ | RARA | P10276 | 10/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026052 | 0.88 | RARB (0.41) | CYP3A4RARBRARGRARARXRA | |
| SCHEMBL8026053 | 0.85 | RARA (0.53) | CYP3A4RARBRARGRARARXRA | |
| SCHEMBL8026706 | 0.84 | CYP3A4 (0.42) | CYP3A4RARBRARGRARARXRA | |
| SCHEMBL8028151 | 0.79 | RARB (0.62) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL8032216 | 0.75 | RARB (0.55) | RARBRARGRARARXRARXRB | |
| SCHEMBL8026383 | 0.74 | CYP3A4 (0.42) | CYP3A4RARBRARGRARARXRA | |
| SCHEMBL6086597 | 0.73 | RARB (0.44) | RARBRARGRARAMAPTPDK2 | |
| SCHEMBL7422927 | 0.72 | RXRA (0.70) | CYP3A4RARBRARGRARARXRA | |
| SCHEMBL8026629 | 0.72 | RARB (0.43) | CYP3A4RARBRARGRARARXRA | |
| SCHEMBL6810972 | 0.72 | RARA (0.39) | CYP3A4RARBRARGRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059861-A1 | SELECTIVE RETINOIC ACID ANALOGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |