Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048974 | 0.85 | AKR1C3 (0.40) | ALDH1A1PTGS1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL10333744 | 0.77 | MAPT (0.43) | ALDH1A1ALOX15 | |
| SCHEMBL8607500 | 0.75 | SMN1; SMN2 (0.42) | ALDH1A1ALOX15 | |
| SCHEMBL3028484 | 0.73 | CES2 (0.46) | ALDH1A1PDE2A | |
| SCHEMBL8041947 | 0.73 | THRA (0.32) | — | |
| SCHEMBL8890469 | 0.70 | FFAR4 (0.39) | ALDH1A1AKR1C2 | |
| SCHEMBL11006226 | 0.69 | KMT2A (0.47) | ALDH1A1ALOX15 | |
| SCHEMBL8048879 | 0.69 | CES2 (0.37) | ALDH1A1 | |
| SCHEMBL3440670 | 0.69 | HTT (0.51) | ALDH1A1ALOX15 | |
| SCHEMBL1194373 | 0.67 | TSHR (0.37) | ALDH1A1PDE2APTGS1PTGS2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140528-A | ALKYL PENTAFLUOROSULFANYL-SUBSTITUTED-BENZOATES | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-10-31 | — | — | US | disclosed |
| US-6013805-A | USED AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-01-11 | — | — | US | disclosed |
| US-5849928-A | Herbicidal isoxazole and 2-cyano-1,3-dione compounds | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-12-15 | — | — | US | disclosed |