Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018549 | 0.83 | CHRM2 (0.42) | ALDH1A1MAPTL3MBTL1KDM4ETRPM8 | |
| SCHEMBL8034147 | 0.78 | SMN1; SMN2 (0.47) | ALDH1A1MAPTL3MBTL1KDM4ETRPM8 | |
| SCHEMBL6032828 | 0.75 | POLB (0.49) | L3MBTL1TSHRSLC6A4MEN1KMT2A | |
| SCHEMBL8018556 | 0.74 | SLC6A2 (0.43) | ALDH1A1L3MBTL1KDM4ETSHRCHRM2 | |
| SCHEMBL6292665 | 0.73 | KDM4E (0.50) | ALDH1A1MAPTL3MBTL1KDM4ERAB9A | |
| SCHEMBL11398150 | 0.72 | ACHE (0.51) | ALDH1A1MAPTKDM4ECHRM2MEN1 | |
| SCHEMBL11387106 | 0.70 | MEN1 (0.50) | L3MBTL1TSHRSLC6A2SLC6A4MEN1 | |
| SCHEMBL6507493 | 0.69 | CA1 (0.40) | ALDH1A1MAPTL3MBTL1KDM4ETSHR | |
| SCHEMBL6292851 | 0.69 | RAB9A (0.39) | MAPTL3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL8028205 | 0.68 | SLC6A2 (0.43) | ALDH1A1L3MBTL1KDM4ETSHRCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000073269-A2 | NICOTINE RECEPTOR LIGANDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2000-12-07 | — | — | WO | disclosed |