Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035734 | 0.91 | SMN1; SMN2 (0.55) | LMNASMN1; SMN2HTTNPSR1MAPT | |
| SCHEMBL8035755 | 0.84 | KDM4E (0.45) | LMNASMN1; SMN2HTTMAPTALOX12 | |
| SCHEMBL8031475 | 0.79 | APOBEC3A (0.56) | LMNASMN1; SMN2HTTNPSR1MEN1 | |
| SCHEMBL8033304 | 0.77 | ALDH1A1 (0.63) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL8029605 | 0.76 | MEN1 (0.58) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8889528 | 0.76 | KMT2A (0.63) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL8029885 | 0.76 | ALDH1A1 (0.55) | LMNASMN1; SMN2HTTMAPTMEN1 | |
| SCHEMBL8033271 | 0.74 | KDM4E (0.48) | LMNAHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL8029862 | 0.74 | SMN1; SMN2 (0.58) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL16026512 | 0.74 | ALDH1A1 (0.67) | LMNASMN1; SMN2HTTNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |