Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035755 | 0.90 | KDM4E (0.45) | KDM4EATMALDH1A1IGF1RKMT2A | |
| SCHEMBL8035734 | 0.83 | SMN1; SMN2 (0.55) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL8029621 | 0.81 | LTA4H (0.61) | KDM4EATMALDH1A1IGF1RHTT | |
| SCHEMBL8029920 | 0.76 | LTA4H (0.65) | KDM4EATMIGF1RKMT2AMEN1 | |
| SCHEMBL8020092 | 0.76 | ATM (0.53) | KDM4EATMALDH1A1KMT2AMEN1 | |
| SCHEMBL8031464 | 0.74 | LMNA (0.52) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL8035719 | 0.72 | LTA4H (0.63) | KDM4EATMALDH1A1FAAHLTA4H | |
| SCHEMBL8035768 | 0.72 | SIGMAR1 (0.57) | KDM4EATMALDH1A1FAAHLMNA | |
| SCHEMBL8020078 | 0.71 | LTA4H (0.65) | KDM4EATMALDH1A1KMT2AMEN1 | |
| SCHEMBL8029940 | 0.71 | SIGMAR1 (0.52) | KDM4EATMALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |