Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033304 | 0.91 | ALDH1A1 (0.63) | SMN1; SMN2ALDH1A1FAAHKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8889528 | 0.90 | KMT2A (0.63) | SMN1; SMN2ALDH1A1FAAHKMT2AMEN1 | |
| SCHEMBL8029611 | 0.89 | PKM (0.67) | SMN1; SMN2ALDH1A1KDM4EFAAHKMT2A | |
| SCHEMBL8029885 | 0.89 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1KDM4EFAAHKMT2A | |
| SCHEMBL8020109 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1KDM4EFAAHKMT2A | |
| SCHEMBL8029605 | 0.88 | MEN1 (0.58) | SMN1; SMN2ALDH1A1KDM4EFAAHKMT2A | |
| SCHEMBL8020023 | 0.88 | POLB (0.61) | SMN1; SMN2ALDH1A1KDM4EFAAHKMT2A | |
| SCHEMBL8029856 | 0.87 | FAAH (0.62) | SMN1; SMN2ALDH1A1KDM4EFAAHKMT2A | |
| SCHEMBL8029596 | 0.86 | SIGMAR1 (0.62) | SMN1; SMN2ALDH1A1FAAHKMT2AMEN1 | |
| SCHEMBL8031475 | 0.84 | APOBEC3A (0.56) | SMN1; SMN2ALDH1A1KDM4EFAAHKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |