Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSL1 | P33121 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 7/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029874 | 0.99 | ACSL1 (0.43) | ACSL1RORCHDAC6IDH1BCHE | |
| SCHEMBL7160501 | 0.86 | HDAC6 (0.53) | HDAC6F2 | |
| Hydrochloric Acid SCHEMBL8026432 | 0.84 | F2 (0.53) | F2 | |
| Hydrochloric Acid SCHEMBL8016349 | 0.83 | F2 (0.52) | F2 | |
| SCHEMBL8032232 | 0.82 | ACSL1 (0.42) | ACSL1RORCBCHECNR2OPRM1 | |
| SCHEMBL8017278 | 0.81 | ITK (0.51) | ACSL1CNR2ITKAURKAMAP4K4 | |
| SCHEMBL8029791 | 0.81 | RORC (0.45) | ACSL1RORCHDAC6IDH1CNR2 | |
| SCHEMBL8016519 | 0.78 | F2 (0.55) | ACSL1RORCIDH1ITKF2 | |
| SCHEMBL8032174 | 0.76 | F2 (0.58) | ACSL1RORCBCHECNR2F2 | |
| SCHEMBL8015782 | 0.76 | RORC (0.58) | RORCHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |