SCHEMBL8032409

SCHEMBL8032409

CC1=CC(C)c2c1c1ccccc1c1cccc([Ti](C)(C)NC(=O)C3CCCCC3)c21.[SiH4]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.36
P2RX7 Q99572 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HPGD P15428 3/20 0.33
HTT P42858 2/20 0.33
MAPT P10636 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALDH1A1 P00352 3/20 0.32
TSHR P16473 3/20 0.32
KMT2A Q03164 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
RAB9A P51151 3/20 0.32
HSD17B10 Q99714 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7041974 0.78 GAA (0.35) GAAP2RX7SMN1; SMN2HPGDHTT
Hydrochloric Acid SCHEMBL7039902 0.78 GAA (0.35) GAAP2RX7SMN1; SMN2HPGDHTT
SCHEMBL8022750 0.77
SCHEMBL7246533 0.72 P2RX7 (0.38) GAAP2RX7SMN1; SMN2HPGDMAPT
Hydrochloric Acid SCHEMBL7242340 0.61 P2RX7 (0.38) GAAP2RX7SMN1; SMN2HPGDMAPT
Hydrochloric Acid SCHEMBL7174111 0.60
SCHEMBL7622820 0.60 HDAC8 (0.36) GAAP2RX7SMN1; SMN2HPGDNPSR1
SCHEMBL6469289 0.60 HDAC8 (0.36) GAAP2RX7SMN1; SMN2HPGDNPSR1
SCHEMBL5968778 0.59 HPGD (0.37) GAAP2RX7SMN1; SMN2HPGDRAB9A
SCHEMBL5969036 0.59 HPGD (0.37) GAAP2RX7SMN1; SMN2HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6150297-A Cyclopentaphenanthrenyl metal complexes and polymerization process THE DOW CHEMICAL COMPANY (US) 2000-11-21 US disclosed