Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469289 | 0.76 | HDAC8 (0.36) | P2RX7SMN1; SMN2HPGDGAATSHR | |
| SCHEMBL7622820 | 0.76 | HDAC8 (0.36) | P2RX7SMN1; SMN2HPGDGAATSHR | |
| Hydrochloric Acid SCHEMBL7242340 | 0.76 | P2RX7 (0.38) | P2RX7SMN1; SMN2HPGDGAATSHR | |
| SCHEMBL727844 | 0.75 | HDAC8 (0.37) | P2RX7SMN1; SMN2HPGDGAATSHR | |
| SCHEMBL5969036 | 0.74 | HPGD (0.37) | P2RX7SMN1; SMN2HPGDGAARAB9A | |
| SCHEMBL5968778 | 0.74 | HPGD (0.37) | P2RX7SMN1; SMN2HPGDGAARAB9A | |
| SCHEMBL8032409 | 0.72 | GAA (0.36) | P2RX7SMN1; SMN2HPGDGAATSHR | |
| SCHEMBL5968791 | 0.67 | — | — | |
| SCHEMBL5968790 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL7239359 | 0.65 | SMN1; SMN2 (0.37) | P2RX7SMN1; SMN2HPGDGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630545-B2 | Polymerization catalyst of a metal complex with anionic, polycyclic, fused ring ligand system containing at least 4 fused rings, a cocatalyst and a butadiene or pentadiene | THE DOW CHEMICAL COMPANY | 2003-10-07 | — | — | US | disclosed |
| US-20020037981-A1 | Polymerization catalyst of a metal complex with anionic, polycyclic, fused ring ligand system containing at least 4 fused rings, a cocatalyst and a butadiene or pentadiene | DOW CHEMICAL COMPANY | 2002-03-28 | — | — | US | disclosed |