Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10979950 | 0.82 | ALDH1A1 (0.63) | ALDH1A1TAAR1CYP2D6CYP2C19LMNA | |
| SCHEMBL11133917 | 0.82 | ALDH1A1 (0.63) | ALDH1A1TAAR1CYP2D6CYP2C19LMNA | |
| SCHEMBL11078064 | 0.82 | ALDH1A1 (0.63) | ALDH1A1TAAR1CYP2D6CYP2C19LMNA | |
| SCHEMBL11133921 | 0.82 | ALDH1A1 (0.63) | ALDH1A1TAAR1CYP2D6CYP2C19LMNA | |
| SCHEMBL14587455 | 0.81 | ZDHHC20 (0.55) | ALDH1A1TAAR1ZDHHC20KMT2ACYP1A2 | |
| SCHEMBL11142483 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TAAR1ZDHHC20CYP2D6CYP2C19 | |
| SCHEMBL11140662 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TAAR1ZDHHC20CYP2D6CYP2C19 | |
| SCHEMBL8857549 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TAAR1ZDHHC20CYP2D6CYP2C19 | |
| SCHEMBL11142756 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TAAR1ZDHHC20CYP2D6CYP2C19 | |
| SCHEMBL11139011 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TAAR1ZDHHC20CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150133653-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | PHOTOBIOTICS LIMITED (GB) | 2015-05-14 | — | — | US | disclosed |
| US-20120070377-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | PHOTOBIOTICS LIMITED (GB) | 2012-03-22 | — | — | US | disclosed |
| WO-2010106341-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | PHOTOBIOTICS LIMITED (GB) | 2010-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133653-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | SSB, HLA-B, BDKRB1 | ALDH1A1 371/4885TAAR1 1058/4885ZDHHC20 3014/4885 |
| US-20120070377-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | SSB, HLA-B, BDKRB1 | ALDH1A1 278/4885TAAR1 1062/4885ZDHHC20 2842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.