Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.55 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.44 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14587450 | 0.90 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2GFPT1HCAR2KEAP1 | |
| SCHEMBL803250 | 0.81 | ALDH1A1 (0.51) | ZDHHC20ALDH1A1CYP1A2MEN1MAPT | |
| SCHEMBL14587454 | 0.80 | HCAR2 (0.52) | ZDHHC20ZDHHC2GFPT1HCAR2KEAP1 | |
| SCHEMBL1831127 | 0.79 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2GFPT1HCAR2KEAP1 | |
| SCHEMBL1831124 | 0.79 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2GFPT1HCAR2KEAP1 | |
| SCHEMBL1831126 | 0.79 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2GFPT1HCAR2KEAP1 | |
| SCHEMBL11529276 | 0.77 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2GFPT1HCAR2KEAP1 | |
| SCHEMBL11529282 | 0.77 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2GFPT1HCAR2KEAP1 | |
| SCHEMBL11527610 | 0.76 | ZDHHC20 (0.66) | ZDHHC20ZDHHC2GFPT1HCAR2KEAP1 | |
| SCHEMBL11529918 | 0.76 | ZDHHC20 (0.66) | ZDHHC20ZDHHC2GFPT1HCAR2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179907-B2 | Antibiotic compounds | SOMALOGIC OPERATING CO. INC. | 2007-02-20 | — | — | US | disclosed |
| US-7179907-B2 | Antibiotic compounds | SOMALOGIC OPERATING CO. INC. | 2007-02-20 | — | — | US | disclosed |