Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032552 | 1.00 | MAOB (0.45) | MAOBTAAR1MAOADAOSPHK1 | |
| SCHEMBL8096004 | 0.96 | MAOB (0.43) | MAOBTAAR1MAOA | |
| SCHEMBL8096006 | 0.96 | MAOB (0.43) | MAOBTAAR1MAOA | |
| SCHEMBL7755798 | 0.86 | MAOB (0.43) | MAOBMAOA | |
| SCHEMBL7755794 | 0.86 | MAOB (0.43) | MAOBMAOA | |
| SCHEMBL7753101 | 0.85 | MAOB (0.42) | MAOBMAOASPHK1 | |
| SCHEMBL7753104 | 0.85 | MAOB (0.42) | MAOBMAOASPHK1 | |
| SCHEMBL8043882 | 0.84 | TSHR (0.39) | MAOBMAOADAOSLC6A4 | |
| SCHEMBL8043879 | 0.84 | TSHR (0.39) | MAOBMAOADAOSLC6A4 | |
| SCHEMBL9229087 | 0.83 | MAOB (0.51) | MAOBTAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657460-B1 | A silacyclohexane compound, a method of prepraring it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5496501-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0657460-A1 | A silacyclohexane compound, a method of prepraring it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |