SCHEMBL803259

SCHEMBL803259

CCC(OC(=O)c1ccc(-c2ccc(C)cc2)cc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.53
CD274 Q9NZQ7 1/20 0.53
UTS2R Q9UKP6 2/20 0.51
NPSR1 Q6W5P4 2/20 0.50
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SLC6A9 P48067 2/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
UBE2N P61088 1/20 0.41
POLB P06746 1/20 0.41
CES2 O00748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22416005 1.00 PDCD1 (0.53) PDCD1CD274UTS2RNPSR1ESR1
SCHEMBL9499271 0.96 NPSR1 (0.53) PDCD1CD274UTS2RNPSR1ESR1
SCHEMBL21396286 0.93 PDCD1 (0.61) PDCD1CD274UTS2RNPSR1ESR1
SCHEMBL18464124 0.93 PDCD1 (0.61) PDCD1CD274UTS2RNPSR1ESR1
SCHEMBL17231351 0.92 NPSR1 (0.50) PDCD1CD274UTS2RNPSR1ESR1
SCHEMBL6667515 0.89 ESR1 (0.53) PDCD1CD274UTS2RNPSR1ESR1
SCHEMBL9498981 0.89 PDCD1 (0.53) PDCD1CD274UTS2RNPSR1ESR1
SCHEMBL21396365 0.89 ESR1 (0.63) PDCD1CD274UTS2RNPSR1ESR1
SCHEMBL12437080 0.89 ESR1 (0.63) PDCD1CD274UTS2RNPSR1ESR1
SCHEMBL26393228 0.87 PDCD1 (0.51) PDCD1CD274UTS2RNPSR1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 484 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-20240228879-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-07-11 US disclosed
US-20240026223-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-01-25 US disclosed
US-11873438-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-01-16 US disclosed
US-11802243-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2023-10-31 US disclosed
US-11795398-B2 Liquid-crystalline medium and liquid-crystal display comprising the same and compounds MERCK PATENT GMBH (DE) 2023-10-24 US disclosed
US-11788010-B2 Liquid crystal composition and liquid crystal display device comprising the same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-17 US disclosed
US-11788009-B2 Liquid-crystalline medium for use in a switching element MERCK PATENT GMBH (DE) 2023-10-17 US disclosed
US-11781069-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2023-10-10 US disclosed
US-7419705-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2008-09-02 US disclosed
US-7413782-B2 Polymerizing binaphthalene derivatives CHISSO CORPORATION (JP) 2008-08-19 US disclosed
US-20080081133-A1 Trifunctional compound, composition and polymer thereof CHISSO CORPORATION 2008-04-03 US disclosed
US-7335405-B2 Nematic liquid crystal mixtures for use in bistable display devices NEMOPTIC (FR) 2008-02-26 US disclosed
US-20070134447-A1 Lateral a-substituted acrylate compound and polymer thereof CHISSO CORPORATION 2007-06-14 US disclosed
US-20070134440-A1 Lateral oxirane compound and polymer thereof CHISSO CORPORATION 2007-06-14 US disclosed
US-20070034830-A1 Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications. MERCK PATENT GMBH (DE) 2007-02-15 US disclosed
EP-0354655-B1 1-PHENYL-1-PROPANOL DERIVATIVES CHISSO CORPORATION (JP) 1993-04-07 EP disclosed
US-5076947-A Optically active; free from temperature dependence CHISSO CORPORATION (JP) 1991-12-31 US disclosed
EP-0354655-A2 1-Phenyl-1-propanol derivatives CHISSO CORPORATION (JP) 1990-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080081133-A1 Trifunctional compound, composition and polymer thereof OXER1, AFF1, OXGR1 PDCD1 1879/4885CD274 1006/4885UTS2R 4740/4885
US-20070134447-A1 Lateral a-substituted acrylate compound and polymer thereof AFF1, CNKSR1, LEF1 PDCD1 2972/4885CD274 1876/4885UTS2R 4799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.