Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3817682 | 0.96 | TSHR (0.52) | ESR1ESR2PDCD1CD274UTS2R | |
| SCHEMBL9500077 | 0.94 | ALDH1A1 (0.55) | ESR1ESR2PDCD1CD274UTS2R | |
| SCHEMBL9499271 | 0.94 | NPSR1 (0.53) | ESR1ESR2PDCD1CD274UTS2R | |
| SCHEMBL18464124 | 0.94 | PDCD1 (0.61) | ESR1ESR2PDCD1CD274UTS2R | |
| SCHEMBL21396286 | 0.94 | PDCD1 (0.61) | ESR1ESR2PDCD1CD274UTS2R | |
| SCHEMBL1129618 | 0.94 | ESR1 (0.64) | ESR1ESR2PDCD1CD274UTS2R | |
| SCHEMBL9499131 | 0.92 | UTS2R (0.60) | ESR1ESR2PDCD1CD274UTS2R | |
| SCHEMBL9500237 | 0.92 | NPC1 (0.48) | ESR1ESR2PDCD1CD274UTS2R | |
| SCHEMBL9498568 | 0.92 | ALDH1A1 (0.49) | ESR1ESR2PDCD1CD274UTS2R | |
| SCHEMBL9869084 | 0.91 | ALDH1A1 (0.51) | ALDH1A1POLBMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004621-B1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN CHEMICALS LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6485657-B1 | Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer | TEIJIN, LIMITED (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1004621-A1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |