Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22416005 | 0.96 | PDCD1 (0.53) | NPSR1UTS2RNPC1RAB9AESR1 | |
| SCHEMBL803259 | 0.96 | PDCD1 (0.53) | NPSR1UTS2RNPC1RAB9AESR1 | |
| SCHEMBL6667515 | 0.94 | ESR1 (0.53) | NPSR1UTS2RNPC1RAB9AESR1 | |
| SCHEMBL3817682 | 0.90 | TSHR (0.52) | NPSR1UTS2RNPC1RAB9AESR1 | |
| SCHEMBL17231351 | 0.88 | NPSR1 (0.50) | NPSR1UTS2RNPC1RAB9AESR1 | |
| SCHEMBL1129618 | 0.88 | ESR1 (0.64) | NPSR1UTS2RNPC1RAB9AESR1 | |
| SCHEMBL21396286 | 0.88 | PDCD1 (0.61) | NPSR1UTS2RNPC1RAB9AESR1 | |
| SCHEMBL9500077 | 0.88 | ALDH1A1 (0.55) | NPSR1UTS2RNPC1RAB9AESR1 | |
| SCHEMBL18464124 | 0.88 | PDCD1 (0.61) | NPSR1UTS2RNPC1RAB9AESR1 | |
| SCHEMBL9498568 | 0.86 | ALDH1A1 (0.49) | NPSR1UTS2RNPC1RAB9AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |