Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL802785 | 0.92 | ESR1 (0.51) | ESR1ESR2KCNJ1PDE3BPDE3A | |
| SCHEMBL803200 | 0.74 | ESR1 (0.62) | ESR1ESR2KCNJ1PGRKCNH2 | |
| SCHEMBL802620 | 0.73 | ESR1 (0.43) | ESR1ESR2KCNJ1KCNH2 | |
| SCHEMBL6830103 | 0.71 | ESR1 (1.00) | ESR1ESR2KCNJ1KCNH2 | |
| SCHEMBL22650585 | 0.66 | ESR1 (0.51) | ESR1ESR2KCNJ1PGR | |
| SCHEMBL21451571 | 0.66 | ESR1 (0.51) | ESR1ESR2KCNJ1PGRKCNH2 | |
| SCHEMBL803047 | 0.65 | ESR1 (0.50) | ESR1ESR2KCNJ1PGRKCNH2 | |
| SCHEMBL14985614 | 0.63 | ESR1 (0.41) | ESR1ESR2PGR | |
| SCHEMBL23284915 | 0.63 | ESR1 (0.44) | ESR1ESR2MAPTPARP10PARP11 | |
| SCHEMBL13377972 | 0.62 | NPC1 (0.48) | ESR2MAPTPARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096795-B2 | Liquid crystal display | MERCK PATENT GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| US-20120069289-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120069289-A1 | LIQUID CRYSTAL DISPLAY | LPXN, VCL, ACP3 | ESR1 1013/4885ESR2 2665/4885KCNJ1 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.