Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 7/20 | 0.35 |
| ▸ | PGR | P06401 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23849173 | 0.89 | ESR1 (0.46) | ESR1ESR2KCNJ1PGR | |
| SCHEMBL22650585 | 0.86 | ESR1 (0.51) | ESR1ESR2KCNJ1PGR | |
| SCHEMBL23289004 | 0.85 | ESR1 (0.42) | ESR1ESR2KCNJ1KCNH2 | |
| SCHEMBL803200 | 0.85 | ESR1 (0.62) | ESR1ESR2KCNJ1PGRKCNH2 | |
| SCHEMBL22644204 | 0.82 | ESR1 (0.43) | ESR1ESR2KCNJ1KCNH2 | |
| SCHEMBL14883956 | 0.75 | PSMB5 (0.49) | ESR1ESR2KCNJ1 | |
| SCHEMBL802785 | 0.72 | ESR1 (0.51) | ESR1ESR2KCNJ1PGR | |
| SCHEMBL803047 | 0.71 | ESR1 (0.50) | ESR1ESR2KCNJ1PGRKCNH2 | |
| SCHEMBL15036782 | 0.71 | KCNJ1 (0.64) | KCNJ1KCNH2ACHESSTR1SLC6A4 | |
| SCHEMBL22644205 | 0.69 | PGR (0.40) | ESR1ESR2KCNJ1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481916-B1 | ELECTRONIC SWITCH | MERCK PATENT GMBH (DE) | 2021-11-03 | — | — | EP | disclosed |
| US-20210257569-A1 | METHOD FOR PRODUCING AN ELECTRONIC COMPONENT WHICH INCLUDES A SELF-ASSEMBLED MONOLAYER | MERCK PATENT GMBH (DE) | 2021-08-19 | — | — | US | disclosed |
| US-11063227-B2 | Electronic switching element | MERCK PATENT GMBH (DE) | 2021-07-13 | — | — | US | disclosed |
| WO-2020225398-A1 | AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2020-11-12 | — | — | WO | disclosed |
| US-20190312216-A1 | ELECTRONIC SWITCHING ELEMENT | MERCK PATENT GMBH (DE) | 2019-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210257569-A1 | METHOD FOR PRODUCING AN ELECTRONIC COMPONENT WHICH INCLUDES A SELF-ASSEMBLED MONOLAYER | SPIN1, EFNA1, SPIN2B | ESR1 315/4885ESR2 113/4885KCNJ1 2286/4885 |
| US-11063227-B2 | Electronic switching element | DNMT3A, DNMT1, DNMT3B | ESR1 25/4885ESR2 48/4885KCNJ1 4019/4885 |
| US-20190312216-A1 | ELECTRONIC SWITCHING ELEMENT | DNMT3A, DNMT1, TET1 | ESR1 25/4885ESR2 139/4885KCNJ1 3399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.