Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032818 | 0.90 | HSP90AA1 (0.39) | RAB9AL3MBTL1LMNAMAPTNPC1 | |
| SCHEMBL8711423 | 0.87 | GAA (0.37) | RAB9AL3MBTL1LMNAMAPTNPC1 | |
| SCHEMBL8033176 | 0.86 | HSP90AA1 (0.44) | RAB9ALMNAMAPTNPC1HSP90AA1 | |
| SCHEMBL8052354 | 0.84 | L3MBTL1 (0.46) | RAB9AL3MBTL1LMNAMAPTNPC1 | |
| SCHEMBL8042769 | 0.84 | AKR1B1 (0.40) | LMNAMAPTNPC1HSP90AA1HSP90AB1 | |
| SCHEMBL8041887 | 0.84 | HSP90AA1 (0.47) | RAB9ALMNAMAPTNPC1HSP90AA1 | |
| SCHEMBL8042634 | 0.82 | HSP90AA1 (0.52) | RAB9ALMNAMAPTHSP90AA1HSP90AB1 | |
| SCHEMBL8044113 | 0.80 | F2RL3 (0.44) | RAB9ALMNAMAPTNPC1HSP90AA1 | |
| SCHEMBL8038020 | 0.77 | P2RX7 (0.44) | RAB9ALMNAMAPTNPC1HSP90AA1 | |
| SCHEMBL8045061 | 0.77 | F2RL3 (0.42) | RAB9ALMNAMAPTNPC1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |