Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 6/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12846569 | 0.83 | AKR1C3 (0.43) | PRKCIAKR1C3AKR1C2AKR1C1AKR1B10 | |
| SCHEMBL7412365 | 0.80 | PRKCI (0.42) | PRKCICYP3A4HDAC3 | |
| SCHEMBL7410812 | 0.80 | HSD11B1 (0.52) | PRKCICYP2C19CYP3A4CYP2C9HDAC3 | |
| SCHEMBL2450173 | 0.77 | APP (0.47) | AKR1C3AKR1C2AKR1C1AKR1B10AKR1C4 | |
| SCHEMBL12846323 | 0.77 | AKR1C3 (0.40) | AKR1C3AKR1C2AKR1C1AKR1B10AKR1C4 | |
| SCHEMBL7412565 | 0.77 | HCAR3 (0.57) | AKR1C3AKR1C2AKR1C1AKR1B10AKR1C4 | |
| SCHEMBL7415701 | 0.76 | HDAC1 (0.41) | PRKCIHDAC3 | |
| SCHEMBL7980982 | 0.74 | OPRM1 (0.45) | — | |
| SCHEMBL21968864 | 0.71 | AKR1C1 (0.49) | AKR1C3AKR1C2AKR1C1AKR1B10AKR1C4 | |
| SCHEMBL23250799 | 0.71 | AKR1C1 (0.39) | AKR1C3AKR1C2AKR1C1APPCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |